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KMID : 0385920090200060732
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Journal of the Korean Society of Emergency Medicine
2009 Volume.20 No. 6 p.732 ~ p.737
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A Case of Successful Management of Paraquat Poisoning with Severe Pulmonary Fibrosis
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Min Jae-Hoon
Lee Ji-Ae
Choi Won-Suk
Kim Hyang
Kang Myung-Soo
Jun Kyung-Hong
Jung Won-Mo
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Abstract
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Paraquat, a potent herbicide, has caused many fatalities through indiscriminate use and suicides. With ingestion of more than one mouthful of 20% paraquat, death is usually caused by pulmonary fibrosis. We experienced a case of paraquat poisoning with severe pulmonary injury. The patient had swallowed about two mouthfuls of 24% commercial paraquat. Hemoperfusion was done within a few hours after ingestion, and then combination therapy with several antioxidants, steroids, and diuretics was given. Initially, ground glass opacities, consolidation, and irregular lines appeared in the patient’s high resolution computed tomography (HRCT). Several months later, lung lesions had improved. The improvement has continued until recently.
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KEYWORD
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Paraquat, Pulmonary fibrosis, Hemoperfusion
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